

✨ Clear skin, no compromises. Spot treat like a pro! ✨
Differin Acne Spot Treatment harnesses the power of 10% benzoyl peroxide—the strongest OTC concentration—to rapidly reduce acne size and redness after one use. This fast-acting, four-in-one formula not only treats and prevents acne but also kills bacteria and improves skin texture, all while glycerin minimizes dryness. Perfect for acne-prone skin, it integrates easily into daily skincare routines for visible, lasting results.












| ASIN | B0D355W5F2 |
| Best Sellers Rank | #3,487 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #110 in Facial Serums |
| Customer Reviews | 4.5 4.5 out of 5 stars (783) |
| Item model number | 0299.053078 |
| Manufacturer | Galderma |
| Package Dimensions | 6.42 x 2.68 x 1.65 inches; 1.76 ounces |
| UPC | 302994611003 |
S**E
Highly effective
I think this product just goes to show that just because a product is expensive or from major brand doesn’t mean it’s the best. I have tried a gazillion products and different price points and I can confidently say this is probably the best I’ve ever had. Not only is it effective it is also very effective. I would say you need to use it for atleast 6 months. Consistency beats intensity.
T**R
Got Rid of My Bump Quickly
I had a bump on my body that would not go away. After some research I was convinced this was the product that would finally get rid of it. I was thrilled once I got my hands on this spot treatment, as it worked within 48 hours. I noticed the bump getting smaller and smaller each day. This was worth every penny, as it was truly effective for my use case. I’d buy it again, however a little bit of this stuff goes a long way, making it a good value.
J**K
Healed 75% of my acne in 12hrs
This got rid of my acne in less than a day. Put this on my forehead acnes at 11am, looked in the mirror at 11pm and my acne was 75% reduced. Its amazing it can work so fast in 12hrs.
R**A
Fast-Acting and Reliable — A Skincare Must-Have
This acne spot treatment is the real deal. I apply it at night on any new breakout or red bump, and by the next morning the swelling is noticeably down—sometimes completely gone. It dries clear, doesn’t flake or irritate, and works under makeup when needed. It’s effective without being overly harsh. I have sensitive, acne-prone skin, and this treatment doesn’t cause peeling or dryness like some others I’ve tried. A little goes a long way, so the tube lasts a while. It’s become my go-to for stopping pimples in their tracks. Whether it's a surprise breakout or a stubborn blemish, this stuff handles it fast. Definitely one of the best spot treatments I’ve used—highly recommend.
E**A
Works wonders
These patches work really well! They stay on overnight and noticeably reduce redness and size by morning. A must-have for quick spot treatment.
L**E
Amazinnnnggg
Absolute miracle!!! Had a variety of acne and some that were under the skin bumps that were tormenting me forever this cleared it up in two days and it hasn't come back since. Love it!
C**R
Really works!
Normally don’t write reviews, but felt I need to considering it changed my life! (No exaggeration) I was so extremely insecure about my skin and I have only been using the product for an entire week and saw a HUGE improvement!!! I am now happy, confident and glowing! I will say, the product does cause some dryness but it is not enough for me to stop using it and using a moisturizer twice a day has really helped!! I am also using the Differin Retinol Gel as well!
F**Y
Best OCT acne treatment for me
Great product. Although I am an older adult I find I still struggle with acne. Differing works for my consistently!
S**A
I received a fake product. The tube had no seal on it. And i bought it for 100 SAR. The audacity to sell fake product in the name of orignal for an orignal price.
Trustpilot
1 day ago
3 weeks ago