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๐พ Stay ahead of pests with the #1 trusted flea & tick shield!
Frontline Plus Flea & Tick Spot Treatment for Large Breed Dogs (45-88 lbs) delivers fast, waterproof, and month-long protection against fleas, ticks, chewing lice, and mange. Featuring active ingredients fipronil and (S)-methoprene, it kills all flea life stages and ticks, trusted by pet owners for over 20 years. Easy to apply and effective even after swimming or bathing, this treatment ensures your large dog stays pest-free and comfortable all month long.


















| ASIN | B0002J1FOE |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Abalone Free |
| Best Sellers Rank | #131 in Pet Supplies ( See Top 100 in Pet Supplies ) #2 in Dog Flea Drops |
| Brand | Frontline |
| Brand Name | Frontline |
| Customer Reviews | 4.4 out of 5 stars 50,244 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00350604287209 |
| Included Components | Package includes 3 applicators |
| Item Form | Liquid |
| Item Type Name | Topical Purple box |
| Item Volume | 339 Milliliters |
| Item Weight | 0.04 Pounds |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | P004FLTSP-45-88 |
| Model Number | 72219 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 350604287209 666672366389 |
| Unit Count | 1 Count |
| Volume | 339 Milliliters |
| Warranty Description | only for dog |
C**P
Stopped his biting fleas better than the prescription product
After spending all kinds of money on, I put Frontline Plus on my Husky/Australian Cattle Dog mix after Next Guard II failed to work for him. Other than trying to rub it off (I kept him inside for 2 hours) he completely stopped scratching within 24 hours. He has a double coat of thick fur so rubbing it in real good to get it down to his skin was key. There were no adverse reactions at all. No smell. No odor. I highly recommend Frontline Plus Flea and Tick. May not work on every dog, but it exceeded my expectations on my dog.
R**Z
Finally found something that actually works!
After trying at least four different flea treatments that barely made a dent, I'm so relieved to have found these drops. They actually work - and work fast. We have two dogs who love being outside, and fleas have been an ongoing battle, especially during the warmer months. Within 24 hours of applying these drops, I noticed a huge difference. The scratching stopped, and when I checked them over, the fleas were gone. It's been several weeks now and still no sign of them coming back. Application is easy - just part the fur at the back of the neck and squeeze the tube. My dogs don't seem bothered by it at all, and it dries quickly so they can go about their day. The protection lasts the full month as advertised, which is more than I can say for some of the other brands we've tried. I've set up a subscription so I never run out because I'm not going back to the constant scratching and discomfort my pups were dealing with before. If you've been struggling to find an effective flea treatment, I highly recommend giving these a try. They've been a game-changer for us. Worth every penny for the peace of mind and happy, comfortable dogs!
A**R
Gets the job done!
Keeps the icky things off! Convenient and easy to use!
J**O
Not sure of effectiveness on Florida fleas
Applied to dog 3 days ago and he is still scratching. Not sure about effectiveness on Florida fleas. No smell to speak of and no hair loss . He was a bit lethargic for the first day but went back to his old crazy self by day 2.
J**D
Works Great!
I have so far been using this for three months and Iโve not found a flea yet. And I did find a tick, but it was not attached to the dog. It was on top of his coat. The stuff so far is working very good.
S**L
Luna has been on it for years
Luna has been on this for many years and she has remained heart worm free. Itโs expensive but itโs worth it.
S**L
Didn't prevent fleas but Seresto collar did
The Frontline Plus flea and tick control for 45 to 88 pound dogs was worse than a disappointment. My dog is 50 pounds--well within the dosage range and become infested with fleas during the second month/dosage of usage. I'm not sure if the preventative actually worked the first month or if I just didn't notice the fleas until the fleas had multiplied enough for me to easily see them. I also don't know if I received the same quailty Frontline product through Amazon as a store/vet purchase. I have no reason to think that this was an imitation product other than some suspicions by other reviewers. Regardless, I had to use a flea dip and flea bomb my house. Once an infestation occurs, getting rid of the fleas is quite an aggravation. I'm trying Advantage II from PetSmart now to see if that will work. Hopefully, something will. June 24 2013, Advantage II didn't work either. I've had acceptable success from Certifect which I buy from my vet. I've used Certifect for over a year now. These flea and tick drops are made by Frontline but are only sold by prescription or thru a vetinarian. It works great for ticks. I've not had any problems with ticks from the first dosage. For a few days, though, after the dosage, he is a bit lethargic. However, my dog will still pick up fleas. The drops do kill the fleas but don't repel them quickly enough. Many people are having trouble with fleas because of the sucession of mild winters. The flea population isn't culled enough. During the summer months, the fleas just seem to overwhelm the medication and flea dips or additional organic sprays are necessary. I've been told that a new flea and tick pill may now be available. I know the flea pill works but I hadn't used it because I needed something for ticks. If this rumor is true, I'll definately give the pill a try. December 30, 2014. I finally found something that actually works for controlling fleas and ticks for my now 70 pound Labrador/mix. (He was a stray that my family adopted--short hair.) My vet introduced me to a new product (at the time) made by Bayer. It's a flea collar called Seresto that is sold on Amazon. I couldn't believe that a flea collar would really work. But, after having to hire Orkin to get the fleas out of my home, I was willing to try it. It's the best product that I have used for fleas and ticks. It's easy to use. I just put the collar on my dog. In few days all fleas were gone. The only ticks I ever find on my dog are the ones that he picks up during a walk or bush adventure. They are easily brushed off (when I notice them) and never attach. The collar lasts as long as advertised--8 months or in our case 5 months since he likes to swim. Unlike the drops, he is never lethargic afterwards. I have used several of these Seresto collars now and can't recommend them enough. They are sold on Amazon, by veterinarians, and I've seen them at Pet Smart as well.
K**S
Great flea and tick repellent
Works well for flea and ticks
D**S
Four Stars
It was very helpful I managed to get control of the continue scratching on her back
A**H
The best
Very excellent and high quality
S**N
Good.
It works
A**P
Beware!
My dog got extremely ill for 3 days afterwards . Seller doesnโt allow returns!
Trustpilot
5 days ago
2 days ago