---
product_id: 6718847
title: "Itch Relief Cream 500G"
brand: "e45"
price: "C$5989"
currency: NIO
in_stock: true
reviews_count: 8
category: "E45"
url: https://www.desertcart.ni/products/6718847-itch-relief-cream-500g
store_origin: NI
region: Nicaragua
---

# Urea-based deep moisturization 500g large jar for long-lasting relief Dual-action anti-itch + soothing formula Itch Relief Cream 500G

**Brand:** e45
**Price:** C$5989
**Availability:** ✅ In Stock

## Summary

> 🛑 Stop the itch, start the comfort — your skin’s new best friend!

## Quick Answers

- **What is this?** Itch Relief Cream 500G by e45
- **How much does it cost?** C$5989 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.ni](https://www.desertcart.ni/products/6718847-itch-relief-cream-500g)

## Best For

- e45 enthusiasts

## Why This Product

- Trusted e45 brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Dual-Action Power:** Combats itching and irritation simultaneously for all-day comfort
- • **Travel-Ready Size:** Compact 500g jar fits perfectly in your daily essentials kit
- • **Trusted by Thousands:** 4.6-star rating from 3,000+ users who swear by its effectiveness
- • **Deep Moisturizing Boost:** Urea-infused formula restores skin’s natural hydration barrier
- • **Clinically Proven Relief:** Contains lauromacrogols, a topical anesthetic that stops itch fast

## Overview

E45 Itch Relief Cream is a dermatologist-formulated, dual-action treatment designed to soothe itching and irritation caused by eczema, dermatitis, and dry skin conditions. Featuring lauromacrogols for fast anti-itch relief and urea for deep moisturization, this lightweight, non-greasy cream comes in a generous 500g jar, making it ideal for sustained use. Highly rated by thousands, it’s a trusted solution for dry, itchy skin that fits seamlessly into your busy lifestyle.

## Description

E45 Itch Relief Cream contains an anti-itch ingredient, lauromacrogols, which treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions. Formulated with urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable. RB-M-01759.

Review: IT REALLY WORKS’ - HEAVEN in a bottle 🙌🏽🙌🏽🙌🏽🙌🏽 I have been suffering with eczema on both of my hands, of all places since June 2025 and I have literally tried EVERYTHING.. nothing works. Not even the prescribed medication. Long story short I read a post about E45 on Facebook about the same condition I have. Extreme itching, eczema. Yada Yada.. it hasn’t even been 24 hours. I could cry 😭 I know it’s pricey but it’s worth it!
Review: Father in law approved - Bought this for my father in law bc he was itching like crazy!! I think he has excema but won't go get it checked out. He would itch until the point of bleeding. So a friend told me about this cream that helped her. I ordered it and low and behold it worked! He loves it so much the bottle is almost empty and I got it like 6 months ago. It was very effective for him and he stopped itching when he put it on. Will be buying again for him and also no more bleeding thank god!

## Features

- DUAL ACTION TREATMENT – For itching and skin irritation caused by dry skin conditions, eczema, itchy dermatitis, pruritus, scaling skin conditions
- ANTI-ITCHING – E45 Itch Relief Cream contains an anti-itch ingredient, Lauromacrogols, which act as a topical anaesthetic and soothes the itch caused by eczema, dermatitis, pruritus and other dry skin conditions
- MOISTURISING - E45 Itch Relief Cream is formulated with Urea, a moisturiser found naturally within the skin so will soothe your skin and leave it feeling calm and comfortable

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B001EJOHUU |
| Active Ingredients | Allergy screened |
| Age Range (Description) | Kid |
| Age Range Description | Kid |
| Best Sellers Rank | #190,213 in Health & Household ( See Top 100 in Health & Household ) #317 in Itching & Rash Treatments #580 in Eczema, Psoriasis & Rosacea Care |
| Brand | E45 |
| Brand Name | E45 |
| Container Type | Jar |
| Country as Labeled | United States |
| Customer Reviews | 4.6 out of 5 stars 3,047 Reviews |
| Item Dimensions | 1.97 x 1.97 x 9.45 inches |
| Item Form | Cream |
| Item Volume | 500 Milliliters |
| Item Weight | 550 Grams |
| Item dimensions L x W x H | 1.97 x 1.97 x 9.45 inches |
| Manufacturer | E45 |
| Manufacturer Part Number | 285-3331 |
| Material Features | Lightweight |
| Material Type Free | Chemical Free |
| Model Name | E45 Dermatological Itch Relief Cream, Moisturising Dual Action Treatment for Itchy and Irritated Skin, 500g |
| Model Number | 348713 |
| Number of Items | 1 |
| Other Special Features of the Product | Travel Size |
| Product Benefits | Anti-itch,Moisturizing,Soothing |
| Recommended Uses For Product | Eczema |
| Scent Name | Cream |
| Skin Care Application Time | Anytime |
| Skin Type | Dry |
| Special Feature | Travel Size |
| Special Ingredients | Eucalyptus Oil |
| Specific Uses For Product | Eczema, allergy |
| Sun Protection | SPF 50 Sun Protection Factor (SPF) |
| Target Use Body Part | Skin |
| Unit Count | 17.64 Ounce |

## Product Details

- **Age Range (Description):** Kid
- **Brand:** E45
- **Item Volume:** 500 Milliliters
- **Item dimensions L x W x H:** 1.97 x 1.97 x 9.45 inches
- **Special Feature:** Travel Size

## Images

![Itch Relief Cream 500G - Image 1](https://m.media-amazon.com/images/I/51Y6C5624FL.jpg)

## Questions & Answers

**Q: does this help bug bites ?**
A: It will stop the itchiness that comes with the bug bite, but will not heal the bite itself.

## Customer Reviews

### ⭐⭐⭐⭐⭐ IT REALLY WORKS’
*by W***S on January 4, 2026*

HEAVEN in a bottle 🙌🏽🙌🏽🙌🏽🙌🏽 I have been suffering with eczema on both of my hands, of all places since June 2025 and I have literally tried EVERYTHING.. nothing works. Not even the prescribed medication. Long story short I read a post about E45 on Facebook about the same condition I have. Extreme itching, eczema. Yada Yada.. it hasn’t even been 24 hours. I could cry 😭 I know it’s pricey but it’s worth it!

### ⭐⭐⭐⭐⭐ Father in law approved
*by H***A on October 11, 2025*

Bought this for my father in law bc he was itching like crazy!! I think he has excema but won't go get it checked out. He would itch until the point of bleeding. So a friend told me about this cream that helped her. I ordered it and low and behold it worked! He loves it so much the bottle is almost empty and I got it like 6 months ago. It was very effective for him and he stopped itching when he put it on. Will be buying again for him and also no more bleeding thank god!

### ⭐⭐⭐⭐⭐ Fantastic Lotion!
*by P***S on July 24, 2012*

I've developed a mild eczema on my hands, arms and ankles and got a steroid cream prescription. When traveling home from England, Heathrow confiscated my steroid cream from my purse and forced me to put in my luggage even though a prescription label was clearly affixed to the tube. To try and cope on the flight, I bought a small tube of E45 Itch Relief at the airport drugstore, and was surprised at how it calmed down the red patches on my hands. I used up the tube at work over several months, and amazingly have now got down to using the steroid cream maybe once a month or so with a bad flare up. After reading how steroid cream can cause long term serious side effects, I combine this with a heavy Eucerin emollient on top at night. When the tube ran out, I bought this big 500g jar. I'm terrified to be without it as it has really reduced my use of the steroid cream.

## Frequently Bought Together

- E45 Itch Relief Cream 500G
- E45 Wash Cream 250ml
- E45 shower cream 200ml

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*Product available on Desertcart Nicaragua*
*Store origin: NI*
*Last updated: 2026-03-16*