







❤️ Elevate your heart game with science-backed TMG power!
Life Extension TMG delivers a pure, scientifically validated dose of trimethylglycine to support healthy homocysteine levels and cardiovascular wellness. This non-GMO, gluten-free, vegetarian supplement is made in the USA and offers flexible dosing options in capsules or powder, making it an essential addition to any heart-conscious or longevity-focused regimen.







| ASIN | B00I509FZI |
| ASIN | B00I509FZI |
| Age Range Description | Adult |
| Allergen Information | Gluten Free, Non-GMO |
| Best Sellers Rank | #6,312 in Health & Household ( See Top 100 in Health & Household ) #118 in Blended Vitamin & Mineral Supplements #750 in Sales & Deals |
| Brand Name | Life Extension |
| Color | Clear |
| Container Type | Bottle |
| Customer Reviews | 4.4 4.4 out of 5 stars (2,138) |
| Date First Available | January 30, 2014 |
| Department | Adults |
| Diet Type | Vegetarian |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00737870185963 |
| Is Discontinued By Manufacturer | No |
| Item Dimensions | 2 x 2 x 3.75 inches |
| Item Form | Capsule |
| Item Nype Name | Trimethylglycine Supplement |
| Item Weight | 3.2 ounces |
| Item model number | 01859 |
| Manufacturer | Life Extension |
| Manufacturer | Life Extension |
| Manufacturer Part Number | 01859 |
| Material Features | Vegetarian |
| Material Type Free | Gluten Free, Non-GMO |
| Model Name | TMG |
| Model Number | 01859 |
| Number of Items | 1 |
| Primary Supplement Type | Trimethylglycine (TMG) |
| Product Benefits | Encourages whole-body health, Helps inhibit inflammatory factors to encourage cardiovascular health, Helps maintain healthy mitochondrial function, Promotes healthy homocysteine levels already within normal range, Supports already-healthy blood pressure levels |
| Product Dimensions | 2 x 2 x 3.75 inches; 3.2 ounces |
| Special Ingredients | Trimethylglycine (TMG) |
| Specific Uses For Product | Heart Health |
| Total Servings Per Container | 30.0 |
| UPC | 737870185963 |
| Unit Count | 60 Count |
O**A
Clean, Simple, and Effective
This Life Extension TMG is a solid, no‑nonsense supplement. The capsules are easy to take, the formula is clean, and it fits well into a daily routine. A reliable option if you want straightforward support without any unnecessary additives.
P**O
Essential Companion to NMN in My Longevity Stack
The primary reason for adding TMG when using NMN or NR is because they increase intracellular NAD⁺ levels which accelerates the activity of methyltransferase enzymes. This can create a significant demand for methyl groups and temporarily elevate homocysteine if methyl donors are insufficient. TMG serves as a methyl donor directly converting homocysteine back to methionine via the betaine-homocysteine methyltransferase pathway. Two capsules with breakfast provide exactly the 1–1.5 g range frequently cited in longevity-focused protocols. For anyone incorporating NMN, NR, or high-dose niacin into a longevity regimen, I consider TMG essential for maintaining methylation balance and minimizing potential homocysteine elevation. This particular TMG offering from Life Extension delivers reliable purity, potency, and value.
B**N
Lowered my BP
Life changing results for my blood pressure
K**C
Helps me absorb vitamins better.
The difference is amazing! I started taking this to help with better absorption of my vitamins. I notice a huge difference and I feel better since taking it. I feel my health is much better since taking this. I feel like I can finally feel the benefits of my B complex vitamins. I take two in the morning with my b complex vitamins (Thorne MethlGaurdPlus) on an empty stomach with no problem. No upset to my stomach. I’ve been taking for a few months now without any issues. Great price and quality. Easy enough to swallow. A must have if you have Issues with methylation that are common with gene mutation.
N**E
Great Product
TMG by Life Extension is the best. I tried the powdered capsule from another brand and hated it. Something about the liquid capsule form and the quality of the product makes me feel better throughout the day. I would highly recommend you give this one a try!
M**A
Good product but ongoing problem with leaky capsules
I bought this product about 6 times and the most recent bottles have had leaky capsules. The liquid gets all over the other pills, so I can't put them in my pill boxes. I am going to look for a replacement even though I really like this one.
J**L
Quality product, experiencing good effects
Appears to be good clean quality and transparent capsules where you can see the product. I took a methylation test a while back and discovered partial COMT varient issues. In taking these I notice a sustained energy throughout the day. Not sure if it's just a coincidence at this point but I will be continuing with this brand's tmg.
K**E
Easy to swallow, no weird taste or odor
Arrived in excellent condition—yes these are liquid filled capsules. A couple reviews had issues with that, wonder if it was particularly hot out if capsules leaked. They are carefully packaged with cotton fluff too. Mine are fully intact, it’s cool weather today and I retrieved them almost immediately on delivery.
N**.
Effective! My 4th or 5th bottle!
A**A
Las pildoras vienen mojadas y llenas de granitos. Parace que algunas de ellas explotaron y embarraron a las demás. No lo vuelvo a comprar
L**A
Great! Using to lower my Homocysteine levels!
A**M
The pill size is so large, that it is not comfortable to swallow (with water ofc).
U**H
Me encanta, buena relación precio/ calidad
Trustpilot
Hace 2 semanas
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